SleepImage announces new article published in Sleep and Breathing


Press Release
February 23, 2019

Title:
Objective Sleep Quality and Metabolic Risk in Healthy Weight Children Results from the randomized Childhood Adenotonsillectomy Trial (CHAT).
 
Link to Publication:
https://doi.org/10.1007/s11325-019-01802-w
 
Introduction:
Previous research on metabolic risk in children has been primarily focused on sleep duration and overweight and/or obese children, rather than sleep quality and healthy weight children.
 
Interesting Findings:
SQI captures differences in sleep apnea and cardiovascular & cardiometabolic parameters, with significant correlations:
Arousal Index (p<0.003) Triglyceride Levels (p<0.019)
Average Heart Rate During Sleep (p<0.022) Triglyceride-HDL Ratio (p<0.008)

 
For each SQI unit increase there is significant decrease in:
  • Average Heart Rate During Sleep (0.154 unit)
  • Insulin Levels (0.109 unit)
  • Triglyceride Levels (0.332 unit)
     
Important Conclusions:
1.Cardiopulmonary Coupling (CPC) Sleep Quality Index (SQI) provides information on augmented autonomic response during sleep and may better capture cardiovascular and cardiometabolic risk than weight group differences alone.
 
2.Low sleep quality in childhood increases risk of cardiovascular and cardiometabolic disease irrespective of weight. Healthy weight children with low sleep quality demonstrate compromised cardiovascular and cardiometabolic profiles when compared to children with high sleep quality, negatively affecting long-term health and well-being.
 
3.Statistically significant and stronger correlation was presented between SQI and the arousal index than between the Apnea Hypopnea Index (AHI) and the arousal index, as children have less collapsible upper airways and less prominent desaturations than adults.
 
4.SQI has demonstrated informative value to improve understanding of pediatric sleep health. Using objective measures of sleep quality and quantity on a regular basis may improve and guide intervention strategies and reduce metabolic risk in children.